Can Ketamine Aid Mental Health & Restore Your Appetite?

September 18, 2025 at 11:01 PM
The Independent

Ketamine-based therapies are emerging as promising treatments for depression, PTSD, and substance abuse, with the Royal College of Psychiatrists endorsing their use under professional oversight. Esketamine, a nasal spray derived from ketamine, has been approved for treatment-resistant depression in Scotland, though its availability remains limited elsewhere in the UK. While psychedelics like MDMA and psilocybin show potential in early studies, experts stress the importance of rigorous research and caution against unregulated use. For residents in Malta, mental health intersects with lifestyle choices, including the Mediterranean diet, known for its mood-enhancing benefits. Nutrient-rich meals and communal dining traditions offer natural support for emotional resilience, complementing innovative therapies. Globally, attitudes toward psychedelic-assisted treatments are shifting, with countries like Australia and Canada paving the way for clinical applications. Proper guidance and professional care remain essential for safe and effective use of these therapies, underscoring the importance of informed decisions in mental health care.

Exploring Innovative Approaches to Mental Health: Ketamine’s Role in Treating Depression

In recent years, the global conversation around mental health has shifted significantly, with experts calling for the development of new and effective treatments for conditions such as depression, PTSD, and substance abuse. Among these emerging therapies, ketamine-based medication has garnered attention for its potential to rapidly alleviate depressive symptoms when administered in controlled clinical settings. The Royal College of Psychiatrists (RCPsych) has officially endorsed its use, emphasizing the importance of rigorous research and professional oversight.

For those in Malta striving to maintain a healthy lifestyle—whether through nutritious food, regular exercise, or mindful dining—mental health is an essential component of overall well-being. Depression and anxiety can affect not only emotional health but also physical wellness, including appetite, digestion, and the motivation to stay active. Understanding the latest advancements in mental health treatments can empower individuals to make informed choices about their care.

Ketamine and Psychedelic Therapies: A New Frontier

In its latest position statement, RCPsych outlined the promising role of pharmacological versions of hallucinogens, including ketamine and MDMA, in treating mental health disorders. Ketamine, in particular, stands out as one of the most studied substances for the rapid relief of depressive symptoms, supported by large randomized controlled trials. Thousands of patients worldwide have participated in research exploring its effects, not only on depression but also on conditions like obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and substance abuse related to alcohol and cocaine. These studies are paving the way for innovative therapies that address the complexities of mental health.

One notable development is the introduction of esketamine, a nasal spray derived from ketamine, which is licensed in the UK for treatment-resistant depression. While available on the NHS in Scotland, it has yet to be rolled out in England. The RCPsych has recommended the use of ketamine in specialist settings with appropriate oversight and long-term monitoring, ensuring patient safety and maximizing therapeutic benefits.

Psychedelics: Promise and Precaution

While early clinical studies of other psychedelics like LSD, MDMA, and psilocybin (a compound derived from mushrooms) have shown encouraging results, experts caution against jumping ahead of the evidence. Conducting adequately blinded trials, managing side effects, and determining whether therapeutic benefits are sustained over time are critical challenges. The RCPsych has emphasized that these substances should not be used in routine clinical practice unless licensed for specific conditions.

Professor Oliver Howes, chairman of RCPsych’s psychopharmacology committee, highlighted the urgent need for new treatments for mental disorders. Current medications, while effective for many, often come with limitations such as delayed action, poor tolerance, or side effects. This gap underscores the importance of exploring alternative therapies like psychedelics, albeit with careful scientific scrutiny.

Mental Health and Lifestyle: The Role of Food and Dining

For those living in Malta—a destination celebrated for its Mediterranean cuisine and vibrant dining culture—mental health and lifestyle choices often intersect. The Mediterranean diet, rich in fresh vegetables, olive oil, whole grains, and lean proteins, has been linked to improved mood and cognitive health. Restaurants across the island are increasingly offering dishes that cater to health-conscious diners, incorporating superfoods, organic ingredients, and plant-based options that support both physical and mental well-being. For individuals recovering from depression or seeking to boost their mood naturally, prioritizing nutrient-dense meals can complement medical treatments like ketamine therapy.

In addition, Malta’s café culture provides opportunities for social connection—a vital factor in mental health. Sharing meals, exploring new restaurants, and engaging with others can enhance emotional resilience and foster a sense of community. For those navigating the challenges of depression or PTSD, these lifestyle elements can serve as valuable adjuncts to clinical care.

A Global Perspective on Psychedelic Treatments

Globally, attitudes toward psychedelic-assisted therapy are evolving. Australia has legislated the use of MDMA and psilocybin for clinical purposes as of July 2023, while Canada and Israel have created pathways for compassionate use of these substances. Research continues into LSD for substance abuse, anxiety, and depression; ketamine-assisted psychotherapy for alcohol dependence; and MDMA-assisted psychotherapy for PTSD. As international legal frameworks change, it’s possible that these therapies could soon become more widely available, including in jurisdictions like Malta.

Still, experts stress the importance of professional guidance. Self-medicating or seeking treatment in unregulated environments can pose significant risks. Properly trained therapists play a crucial role in supporting patients through every step of their journey, from preparation to follow-up care. Psychedelics can profoundly affect the mind, lowering psychological defenses and allowing traumatic material to surface. This vulnerability requires careful handling by experienced practitioners to ensure safe and effective treatment.

Supporting Mental Health Through Food and Connection

For readers interested in food, restaurants, and holistic health in Malta, the intersection of diet, lifestyle, and mental well-being offers an exciting avenue for exploration. From enjoying nutrient-rich meals to embracing the island’s communal dining traditions, there are countless ways to support mental health through everyday choices. As the conversation around innovative treatments like ketamine continues to evolve, staying informed and engaged can help individuals make decisions that align with their overall health goals.

By combining cutting-edge therapies with lifestyle adjustments like mindful eating and social connection, Malta’s residents and visitors can cultivate physical and mental resilience, ensuring a balanced and fulfilling approach to well-being.