Can Food-Linked Weight Loss Drugs Slow Ageing in Malta?

November 21, 2025 at 12:30 PM
The Independent

A recent study suggests that microdoses of popular weight-loss drugs like Ozempic may have potential anti-ageing benefits, though findings are still in early stages and based on research in mice. The study observed that small doses of exenatide, a drug with a similar chemical structure, improved metabolic health markers and mimicked younger molecular profiles in various tissues, with the brain playing a central role. While promising, experts emphasize that human trials are needed to confirm these effects. For those in Malta seeking longevity, focusing on proven lifestyle habits remains key. The Mediterranean diet, rich in vegetables, whole grains, olive oil, and lean proteins, is a cornerstone of Maltese culture and scientifically linked to reducing inflammation and supporting overall health. Malta’s vibrant food scene offers plenty of opportunities to enjoy nutrient-rich meals, from grilled fish to traditional dishes like minestra and kusksu, while practicing mindful eating enhances both physical and mental well-being. While anti-ageing drugs may hold future potential,

Can Low Doses of These Popular Drugs Slow Ageing? What the Science Says

In recent years, the connection between what we consume and how it impacts our health and longevity has gained significant attention. A groundbreaking study now suggests that microdoses of popular weight-loss drugs, such as Ozempic, may play a role in slowing ageing. While the findings are still in their early stages, they open up fascinating discussions about the intersection of food, health, and lifestyle—topics that resonate deeply with those seeking to live healthier, longer lives in Malta.

The Science Behind It
Originally developed to manage diabetes, semaglutide—sold under brand names like Ozempic and Wegovy—has surged in popularity globally due to its efficacy in weight loss. This drug mimics the action of the GLP-1 hormone, naturally produced in the gut, to regulate appetite and promote a sense of fullness. However, recent research from the Chinese University of Hong Kong suggests that another drug with a similar chemical structure, exenatide, might offer benefits that go beyond weight management.

In a study conducted on mice, researchers administered small doses of exenatide to middle-aged mice (approximately 11 months old in mouse years) over a 30-week period. They then measured various biomarkers in tissues such as the brain, liver, kidney, muscles, and adipose tissue. The results showed that the treated mice exhibited metabolic health markers and molecular profiles resembling those of younger, healthier animals.

What Does This Mean for Longevity?
The study revealed that the drug brought about consistent changes in many tissues, counteracting typical patterns of ageing. Interestingly, the brain appeared to play a central role, acting as a hub that influenced the ageing profiles of other organs. While the research is promising, it’s crucial to note that these findings were observed in mice, not humans. Whether these drugs have the same anti-ageing effects in people remains to be proven through larger clinical trials.

A Balanced Approach to Longevity in Malta
While the idea of anti-ageing drugs may sound exciting, experts caution against jumping on trends before solid evidence is available. Instead, those in Malta looking to enhance their longevity can focus on sustainable, research-backed habits that promote both physical and mental well-being.

One of the most powerful ways to support a long and healthy life is through a balanced Mediterranean diet—a cornerstone of Maltese culture. Packed with fresh vegetables, whole grains, healthy fats from olive oil, and lean proteins like fish and legumes, this diet has been scientifically proven to reduce inflammation, support cardiovascular health, and even slow down certain aspects of ageing.

For those dining out, Malta boasts a vibrant food scene with restaurants offering a variety of nutritious options. Whether it’s a freshly grilled catch of the day, a vibrant vegetable-packed plate of kusksu, or a hearty bowl of minestra, the local cuisine provides plenty of opportunities to eat well while enjoying the island’s culinary heritage.

Mindful Eating and Longevity
In addition to what you eat, how you eat can also make a difference. Practicing mindful eating—savouring every bite, eating slowly, and listening to your body’s hunger and fullness cues—can help regulate appetite naturally, much like the effects of GLP-1. This approach not only supports weight management but also enhances your relationship with food, making it a source of nourishment and joy rather than stress.

The Future of Anti-Ageing Science
While researchers are optimistic about the potential of GLP-1-based drugs like Ozempic and exenatide to slow ageing, they caution that much more research is needed. The study was conducted on middle-aged mice, and it’s unclear how these drugs might work in older animals or humans. Moreover, while molecular changes were observed, the study did not confirm whether the drugs could actually reverse ageing in a measurable way.

As scientists continue to explore anti-ageing strategies, including GLP-1 receptor agonists, it’s essential to focus on proven lifestyle factors that contribute to longevity. A combination of healthy eating, regular physical activity, and mental well-being remains the gold standard for those aiming to live a long and fulfilling life.

Eating Well, Living Well in Malta
For anyone in Malta looking to improve their health and longevity, the journey begins on your plate. Explore the incredible diversity of local and international cuisines available at restaurants across the island, many of which offer healthy, nutrient-rich options. Combine this with Malta’s natural opportunities for physical activity—whether it’s a swim in the Mediterranean, a hike along the cliffs, or a yoga session by the sea—and you have a recipe for a life that’s not just longer, but more vibrant.

While the promise of anti-ageing drugs is still on the horizon, the secrets to a healthier, longer life might already be at your fingertips. After all, in Malta, enjoying good food and embracing an active lifestyle is more than a trend—it’s a way of life.